in great confusion vs topsy-turvy

in great confusion is not an adjective while topsy-turvy is an adjective.

Word	Noun	Adjective	Verb	Adverb
in great confusion	No	No	No	Yes
topsy-turvy	No	Yes	No	Yes

As adverbs, in great confusion and topsy-turvy are synonyms defined as:

Other synonyms of in great confusion include head over heels, heels over head, topsy-turvily.

in great confusion (adjective)	topsy-turvy (adjective)
	in utter disorder

in great confusion (adverb)	topsy-turvy (adverb)
in disorderly haste	in disorderly haste
	in a disordered manner