topsy-turvy vs in great confusion

topsy-turvy is an adjective but in great confusion is not an adjective.

Word	Noun	Adjective	Verb	Adverb
topsy-turvy	No	Yes	No	Yes
in great confusion	No	No	No	Yes

As adverbs, topsy-turvy and in great confusion are synonyms defined as:

Other synonyms of topsy-turvy include head over heels, heels over head, topsy-turvily.

topsy-turvy (adjective)	in great confusion (adjective)
in utter disorder

topsy-turvy (adverb)	in great confusion (adverb)
in disorderly haste	in disorderly haste
in a disordered manner