loosen up vs make relaxed

loosen up and make relaxed both are verbs.

Word	Noun	Adjective	Verb	Adverb
loosen up	No	No	Yes	No
make relaxed	No	No	Yes	No

As verbs, loosen up and make relaxed are synonyms defined as:

Other synonyms of loosen up include relax, unlax, unstrain, unwind.

loosen up (verb)	make relaxed (verb)
become less tense, rest, or take one's ease	cause to feel relaxed
cause to feel relaxed
make one's body limber or suppler by stretching, as if to prepare for strenuous physical activity
cause to become unblocked
become less tense, less formal, or less restrained, and assume a friendlier manner