oedema vs puffiness

oedema and puffiness both are nouns.

Word	Noun	Adjective	Verb	Adverb
oedema	Yes	No	No	No
puffiness	Yes	No	No	No

As nouns, puffiness is a hypernym of oedema; that is, puffiness is a word with a broader meaning than oedema:

oedema: swelling from excessive accumulation of watery fluid in cells, tissues, or serous cavities
puffiness: an abnormal protuberance or localized enlargement

Other hypernyms of oedema include lump, swelling.

oedema (noun)	puffiness (noun)
swelling from excessive accumulation of watery fluid in cells, tissues, or serous cavities	lack of elegance as a consequence of being pompous and puffed up with vanity
	an abnormal protuberance or localized enlargement