offspring vs issue

offspring and issue both are nouns.

Word	Noun	Adjective	Verb	Adverb
offspring	Yes	No	No	No
issue	Yes	No	Yes	No

As nouns, issue is a hypernym of offspring; that is, issue is a word with a broader meaning than offspring:

Other hypernyms of offspring include consequence, effect, event, outcome, result, upshot.

As nouns, offspring and issue are synonyms defined as:

Other synonyms of offspring include progeny.

offspring (noun)	issue (noun)
any immature animal	the act of issuing printed materials
something that comes into existence as a result	the act of providing an item for general use or for official purposes (usually in quantity)
the immediate descendants of a person	an opening that permits escape or release
	some situation or event that is thought about
	an important question that is in dispute and must be settled
	one of a series published periodically
	the becoming visible
	the immediate descendants of a person
	a phenomenon that follows and is caused by some previous phenomenon
	the income or profit arising from such transactions as the sale of land or other property
	supplies (as food or clothing or ammunition) issued by the government

offspring (verb)	issue (verb)
	come out of
	prepare and issue for public distribution or sale
	bring out an official document (such as a warrant)
	make out and issue
	circulate or distribute or equip with