run down vs deplete

run down and deplete both are verbs.

Word	Noun	Adjective	Verb	Adverb
run down	No	No	Yes	No
deplete	No	No	Yes	No

As verbs, deplete is a hypernym of run down; that is, deplete is a word with a broader meaning than run down:

Other hypernyms of run down include consume, eat, eat up, exhaust, expend, run through, use, use up, wipe out.

run down (verb)	deplete (verb)
use up all one's strength and energy and stop working	use up (resources or materials)
injure or kill by knocking (someone or something) down and passing over the body, as with a vehicle
pursue until captured
move downward
examine hastily
deplete
trace