alienate vs affect

alienate is not a noun while affect is a noun.

Word	Noun	Adjective	Verb	Adverb
alienate	No	No	Yes	No
affect	Yes	No	Yes	No

As verbs, affect is a hypernym of alienate; that is, affect is a word with a broader meaning than alienate:

Other hypernyms of alienate include impress, move, strike.

alienate (noun)	affect (noun)
	the conscious subjective aspect of feeling or emotion

alienate (verb)	affect (verb)
arouse hostility or indifference in where there had formerly been love, affection, or friendliness	act physically on; have an effect upon
make withdrawn or isolated or emotionally dissociated	have an effect upon
transfer property or ownership	make believe with the intent to deceive
	have an emotional or cognitive impact upon
	connect closely and often incriminatingly