choler vs fretfulness

choler and fretfulness both are nouns.

Word	Noun	Adjective	Verb	Adverb
choler	Yes	No	No	No
fretfulness	Yes	No	No	No

As nouns, choler and fretfulness are synonyms defined as:

Other synonyms of choler include crossness, fussiness, irritability, peevishness, petulance.

choler (noun)	fretfulness (noun)
a humor that was once believed to be secreted by the liver and to cause irritability and anger	an irritable petulant feeling
a strong emotion; a feeling that is oriented toward some real or supposed grievance
an irritable petulant feeling