desecration vs profanation

desecration and profanation both are nouns.

Word	Noun	Adjective	Verb	Adverb
desecration	Yes	No	No	No
profanation	Yes	No	No	No

As nouns, desecration and profanation are synonyms defined as:

desecration and profanation: blasphemous behavior; the act of depriving something of its sacred character

Other synonyms of desecration include blasphemy, sacrilege.

desecration (noun)	profanation (noun)
blasphemous behavior; the act of depriving something of its sacred character	blasphemous behavior; the act of depriving something of its sacred character
	degradation of something worthy of respect; cheapening