misfortune vs destiny

misfortune and destiny both are nouns.

Word	Noun	Adjective	Verb	Adverb
misfortune	Yes	No	No	No
destiny	Yes	No	No	No

As nouns, destiny is a hypernym of misfortune; that is, destiny is a word with a broader meaning than misfortune:

misfortune: an unfortunate state resulting from unfavorable outcomes
destiny: your overall circumstances or condition in life (including everything that happens to you)

Other hypernyms of misfortune include circumstances, fate, fortune, lot, luck, portion.

misfortune (noun)	destiny (noun)
unnecessary and unforeseen trouble resulting from an unfortunate event	an event (or a course of events) that will inevitably happen in the future
an unfortunate state resulting from unfavorable outcomes	the ultimate agency regarded as predetermining the course of events
	your overall circumstances or condition in life (including everything that happens to you)