substrate vs substance

substrate and substance both are nouns.

Word	Noun	Adjective	Verb	Adverb
substrate	Yes	No	No	No
substance	Yes	No	No	No

As nouns, substance is a hypernym of substrate; that is, substance is a word with a broader meaning than substrate:

substrate (noun)	substance (noun)
an indigenous language that contributes features to the language of an invading people who impose their language on the indigenous population	the real physical matter of which a person or thing consists
any stratum or layer lying underneath another	a particular kind or species of matter with uniform properties
a surface on which an organism grows or is attached	the property of holding together and retaining its shape
the substance that is acted upon by an enzyme or ferment	the idea that is intended
	the choicest or most essential or most vital part of some idea or experience
	content communicating a message; what something is about
	considerable capital (wealth or income)
	material of a particular kind or constitution