tire vs run down

tire is a noun but run down is not a noun.

Word	Noun	Adjective	Verb	Adverb
tire	Yes	No	Yes	No
run down	No	No	Yes	No

As verbs, run down is a hyponym of tire; that is, run down is a word with a more specific, narrower meaning than tire:

Other hyponyms of tire include conk out, peter out, poop out, run out, retire, withdraw.

As verbs, tire and run down are synonyms defined as:

Other synonyms of tire include exhaust, play out, sap.

tire (noun)	run down (noun)
hoop that covers a wheel

tire (verb)	run down (verb)
lose interest or become bored with something or somebody	use up all one's strength and energy and stop working
exhaust or get tired through overuse or great strain or stress	injure or kill by knocking (someone or something) down and passing over the body, as with a vehicle
cause to be bored	pursue until captured
deplete	move downward
	examine hastily
	deplete
	trace