despondency vs heartsickness

despondency and heartsickness both are nouns.

Word	Noun	Adjective	Verb	Adverb
despondency	Yes	No	No	No
heartsickness	Yes	No	No	No

As nouns, despondency and heartsickness are synonyms defined as:

despondency and heartsickness: feeling downcast and disheartened and hopeless

Other synonyms of despondency include despondence, disconsolateness.

despondency (noun)	heartsickness (noun)
feeling downcast and disheartened and hopeless	feeling downcast and disheartened and hopeless