fortune vs misfortune

fortune and misfortune both are nouns.

Word	Noun	Adjective	Verb	Adverb
fortune	Yes	No	No	No
misfortune	Yes	No	No	No

As nouns, misfortune is a hyponym of fortune; that is, misfortune is a word with a more specific, narrower meaning than fortune:

fortune: your overall circumstances or condition in life (including everything that happens to you)
misfortune: an unfortunate state resulting from unfavorable outcomes

Other hyponyms of fortune include good fortune, good luck, luckiness, providence, bad luck, ill luck, tough luck, failure.

fortune (noun)	misfortune (noun)
an unknown and unpredictable phenomenon that causes an event to result one way rather than another	unnecessary and unforeseen trouble resulting from an unfortunate event
an unknown and unpredictable phenomenon that leads to a favorable outcome	an unfortunate state resulting from unfavorable outcomes
a large amount of wealth or prosperity
your overall circumstances or condition in life (including everything that happens to you)