significance vs substance

significance and substance both are nouns.

Word	Noun	Adjective	Verb	Adverb
significance	Yes	No	No	No
substance	Yes	No	No	No

As nouns, substance is a hypernym of significance; that is, substance is a word with a broader meaning than significance:

Other hypernyms of significance include meaning.

As nouns, substance is a hypernym of significance; that is, substance is a word with a broader meaning than significance:

Other hypernyms of significance include content, message, subject matter.

significance (noun)	substance (noun)
the quality of being significant	the real physical matter of which a person or thing consists
a meaning that is not expressly stated but can be inferred	a particular kind or species of matter with uniform properties
the message that is intended or expressed or signified	the property of holding together and retaining its shape
	the idea that is intended
	the choicest or most essential or most vital part of some idea or experience
	content communicating a message; what something is about
	considerable capital (wealth or income)
	material of a particular kind or constitution